Human Normal Immunoglobulin IP 16.5% (For IM use)

A highly concentrated, sterile donor antibody solution designed exclusively for deep intramuscular injection to provide rapid passive immunity. It delivers a potent, broad-spectrum dose of IgG antibodies to treat primary immunodeficiency disorders and offer immediate post-exposure protection against infections like Measles and Hepatitis A. Adhering strictly to IP standards, this 16.5% formula ensures a controlled, sustained release of immune defense without entering the bloodstream directly.

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High-Concentration Passive Immunity and Antibody Replacement

Human Normal Immunoglobulin IP 16.5% is a highly concentrated, sterile solution of human antibodies compiled from large pools of healthy donor plasma. This formulation is rigorously manufactured to comply with Indian Pharmacopoeia (IP) standards and is explicitly designated For Intramuscular (IM) Use Only. By delivering a potent dose of broad-spectrum immunoglobulin G (IgG) directly into the muscle tissue, this therapy provides critical protection against serious viral and bacterial infections for patients with compromised immune systems or those requiring immediate post-exposure prophylaxis.

How It Works

Immunoglobulins act as the body's primary defense system to recognize and neutralize foreign pathogens. At a 16.5% concentration, this product offers a much higher density of antibodies per milliliter than standard intravenous solutions. When injected deep into the muscle, the antibodies are gradually absorbed into the bloodstream. This creates a sustained release of passive immunity, temporarily fortifying the body's defenses when it is unable to produce enough antibodies on its own or when rapid protection is needed after exposure to an infectious disease.

Key Applications

Primary Immunodeficiency Diseases (PIDD): Serves as reliable maintenance therapy to replace missing or deficient antibodies in patients prone to recurrent infections.
Hepatitis A Prophylaxis: Used for immediate prevention or attenuation of Hepatitis A infection following close personal contact or travel to high-risk areas.
Measles Prevention: Provides post-exposure prophylaxis to modify or prevent measles in susceptible individuals who have been exposed to the virus.
Hypergammaglobulinemia Support: Assists in balancing antibody levels in specific secondary immunodeficiency states.

Clinical Specifications & Safety

Administration: Must be administered strictly via deep intramuscular injection into large muscle masses (such as the gluteal region or anterolateral thigh). Never inject this formulation intravenously (IV), as high-concentration IM formulas can cause severe reactions if introduced directly into the bloodstream.
Viral Inactivation: Undergoes extensive multi-step purification and rigorous viral screening processes during production to ensure maximum safety and eliminate the risk of blood-borne pathogen transmission.

Important Safety Notice: Due to its high concentration, local soreness, redness, and swelling at the injection site are common. It should be used with extreme caution in patients with a history of isolated IgA deficiency or severe allergic reactions to human plasma products.

Disclaimer: This is a specialized prescription medication. The description provided is strictly for educational purposes and should not substitute professional clinical advice or guidance.